Randy J Seeley Selected Research

Weight Loss (Weight Reduction)

1/2022	Vertical sleeve gastrectomy increases duodenal Lactobacillus spp. richness associated with the activation of intestinal HIF2α signaling and metabolic benefits.
1/2022	Dietary induction of obesity and insulin resistance is associated with changes in Fgf21 DNA methylation in liver of mice.
6/2021	Growth differentiation factor 15 neutralization does not impact anorexia or survival in lipopolysaccharide-induced inflammation.
1/2021	Restructuring of the male mice peripheral circadian network after bariatric surgery.
10/2020	The Role of Elevated Branched-Chain Amino Acids in the Effects of Vertical Sleeve Gastrectomy to Reduce Weight and Improve Glucose Regulation.
1/2020	Nutrient and hormone composition of milk is altered in rodent dams post-bariatric surgery.
1/2020	The Unconventional Role for Gastric Volume in the Response to Bariatric Surgery for Both Weight Loss and Glucose Lowering.
1/2020	Leveraging the Gut to Treat Metabolic Disease.
11/2019	Distinct Neural Sites of GLP-1R Expression Mediate Physiological versus Pharmacological Control of Incretin Action.
10/2019	Glycemic effect of pancreatic preproglucagon in mouse sleeve gastrectomy.

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Randy J Seeley Research Topics

Disease

84	Body Weight (Weight, Body) 01/2021 - 06/2002
78	Obesity 01/2022 - 04/2003
56	Weight Loss (Weight Reduction) 01/2022 - 04/2003
19	Insulin Resistance 01/2022 - 08/2008
17	Type 2 Diabetes Mellitus (MODY) 01/2022 - 12/2005
14	Weight Gain 01/2022 - 02/2003
13	Glucose Intolerance 01/2022 - 10/2007
9	Anorexia 06/2021 - 12/2002
7	Hyperglycemia 01/2020 - 08/2008
7	Hyperphagia (Overeating) 09/2013 - 08/2002
6	Inflammation (Inflammations) 06/2021 - 04/2004
6	AIDS-Related Complex (ARC) 01/2021 - 02/2003
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2020 - 06/2010
3	Neoplasms (Cancer) 01/2022 - 10/2015
3	Ketosis 01/2018 - 12/2008
2	Hypoxia (Hypoxemia) 01/2022 - 01/2022
2	Myocardial Infarction 11/2021 - 08/2014
2	Metabolic Diseases (Metabolic Disease) 01/2018 - 07/2013
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2015 - 09/2010
2	Fatty Liver 01/2015 - 07/2013
2	Non-alcoholic Fatty Liver Disease 11/2014 - 09/2010
2	Hirsutism 06/2014 - 10/2011
2	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 06/2014 - 10/2011
2	Diabetes Mellitus 05/2014 - 06/2011
1	Iron Deficiencies 01/2022
1	Infections 01/2022
1	Nausea 01/2022
1	Stroke (Strokes) 11/2021
1	Atherosclerosis 11/2021
1	Chronic Disease (Chronic Diseases) 06/2021
1	Cachexia 06/2021
1	Sepsis (Septicemia) 06/2021

Drug/Important Bio-Agent (IBA)

57	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 12/2005
26	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2022 - 12/2002
22	Insulin (Novolin)FDA Link 01/2021 - 06/2002
15	LeptinIBA 01/2021 - 06/2002
13	salicylhydroxamic acid (SHAM)IBA 01/2021 - 09/2010
10	Hormones (Hormone)IBA 11/2018 - 02/2005
8	MelanocortinsIBA 05/2015 - 06/2002
7	Bile Acids and Salts (Bile Acids)IBA 01/2018 - 09/2010
7	CarbohydratesIBA 01/2018 - 04/2005
6	Peptides (Polypeptides)IBA 01/2020 - 04/2010
6	Liraglutide FDA Link 01/2019 - 07/2013
5	Glucagon-Like Peptide-1 ReceptorIBA 01/2021 - 08/2008
5	LipidsIBA 02/2020 - 08/2009
5	Leptin ReceptorsIBA 01/2018 - 03/2008
5	GlucocorticoidsIBA 01/2018 - 07/2004
4	Growth Differentiation Factor 15IBA 01/2022 - 01/2019
4	CytokinesIBA 01/2022 - 04/2004
4	fibroblast growth factor 21IBA 01/2022 - 05/2013
4	Glucagon-Like Peptide-1 Receptor AgonistsIBA 11/2021 - 06/2011
4	GhrelinIBA 01/2013 - 12/2005
4	Dietary Fats (Dietary Fat)IBA 01/2013 - 04/2003
4	Messenger RNA (mRNA)IBA 02/2012 - 04/2004
3	LipopolysaccharidesIBA 01/2022 - 04/2004
3	Transcription Factors (Transcription Factor)IBA 01/2022 - 10/2015
3	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 01/2018 - 03/2008
3	CorticosteroneIBA 01/2018 - 11/2005
3	CholesterolIBA 10/2017 - 09/2010
3	IncretinsIBA 10/2017 - 09/2011
3	Biological ProductsIBA 07/2015 - 07/2002
3	Exenatide (Byetta)FDA Link 08/2014 - 10/2007
3	Mechanistic Target of Rapamycin Complex 1IBA 10/2009 - 07/2008
2	Branched-Chain Amino AcidsIBA 10/2020 - 09/2012
2	Triglycerides (Triacylglycerol)IBA 01/2018 - 06/2014
2	Dietary Carbohydrates (Carbohydrate, Dietary)IBA 01/2018 - 11/2013
2	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2018 - 11/2005
2	Glucagon (Glukagon)FDA Link 01/2017 - 05/2013
2	Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA 10/2015 - 09/2013
2	Fatty Acids (Saturated Fatty Acids)IBA 10/2015 - 03/2008
2	Proteins (Proteins, Gene)FDA Link 10/2015 - 01/2008
2	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 09/2013 - 09/2009
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 09/2013 - 09/2009
2	Angiotensin IIIBA 03/2013 - 12/2011
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 10/2009 - 02/2003
2	Agouti-Related ProteinIBA 10/2009 - 02/2003
2	Fatty Acid Synthases (Fatty Acid Synthase)IBA 12/2008 - 11/2002
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 11/2008 - 11/2005
2	Ciliary Neurotrophic Factor (CNTF)IBA 07/2008 - 04/2004
2	apolipoprotein A-IV (apolipoprotein AIV)IBA 12/2004 - 08/2004
1	Metformin (Glucophage)FDA LinkGeneric 01/2022
1	IronIBA 01/2022
1	semaglutideIBA 11/2021
1	Monoclonal AntibodiesIBA 06/2021
1	B-Cell Activating FactorIBA 01/2021
1	Neurotensin Receptors (Neurotensin Receptor)IBA 01/2021
1	Amyloidogenic ProteinsIBA 01/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2021
1	Glial Fibrillary Acidic ProteinIBA 01/2021
1	EnzymesIBA 01/2021

Therapy/Procedure

34	Gastrectomy 01/2022 - 06/2010
34	Bariatric Surgery 01/2021 - 02/2005
20	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2022 - 02/2005
16	Therapeutics 01/2021 - 09/2003
5	Glycemic Control 01/2018 - 01/2015
3	Fat-Restricted Diet (Diet, Fat Restricted) 06/2006 - 04/2003
2	Ketogenic Diet 01/2018 - 10/2015
2	Transplantation 10/2015 - 09/2010
2	Carbohydrate-Restricted Diet (Low Carbohydrate Diet) 03/2005 - 04/2003
2	Adrenalectomy 07/2004 - 12/2003